Open source software is thought to be one of the driving forces in overcoming the fragmentation in the health IT market. However, barriers like lack of long-term professional support [editor’s note: this may be universal for all health IT] or uncertainty of cost saving capability hinders open source software to gain a reasonable market share. The workshop “Open Source in European Health Care” is conceptualized as a forum where existing open source projects or initiatives are invited to present their work or their experiences in the field of open source in health care. Submissions from all over the world including position papers are highly welcome.